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Are immune-mediated diseases risk factors for long COVID?
Safe People
University College London
grid.83440.3b
Dylan Williams
Safe Projects
DAA096_llc_0005
The predisposing factors responsible for individuals developing prolonged duration of COVID-19 symptoms over several months (long COVID) are unknown, but exaggerated inflammatory and autoimmune responses have been proposed as key determinants. Individuals suffering from chronic inflammatory disorders, including atopic conditions and autoimmune diseases, have heightened risk of developing other inflammatory diseases, phenomena known as autoimmune and atopic diatheses. People with a history of atopic and/or autoimmune diseases might also have an increased liability for long COVID following SARS-CoV-2 infection if immune dysregulation is in part or wholly responsible for protracted symptomatology. However, associations between chronic inflammatory diseases and long COVID risk have not been studied rigorously in epidemiological settings to date.
Research
NIHR BioResource Data Access Committee
31/08/2021
Safe Data
De-Personalised
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The individual to whom the information relates has consented
No
One-off
Safe Setting
TRE