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Are immune-mediated diseases risk factors for long COVID?

Safe People

Organisation name

University College London

Organisation ID

grid.83440.3b

Applicant name(s)

Dylan Williams

Safe Projects

Project ID

DAA096_llc_0005

Lay summary

The predisposing factors responsible for individuals developing prolonged duration of COVID-19 symptoms over several months (long COVID) are unknown, but exaggerated inflammatory and autoimmune responses have been proposed as key determinants. Individuals suffering from chronic inflammatory disorders, including atopic conditions and autoimmune diseases, have heightened risk of developing other inflammatory diseases, phenomena known as autoimmune and atopic diatheses. People with a history of atopic and/or autoimmune diseases might also have an increased liability for long COVID following SARS-CoV-2 infection if immune dysregulation is in part or wholly responsible for protracted symptomatology. However, associations between chronic inflammatory diseases and long COVID risk have not been studied rigorously in epidemiological settings to date.

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Research

Other approval committees

NIHR BioResource Data Access Committee

Latest approval date

31/08/2021

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Data sensitivity level

De-Personalised

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(e) processing is necessary for the performance of a task carried out in the public interest or in the exercise of official authority vested in the controller;

Lawful conditions for provision of data under Article 9

(j) processing is necessary for archiving purposes in the public interest, scientific or historical research purposes or statistical purposes in accordance with Article 89(1) based on Union or Member State law which shall be proportionate to the aim pursued, respect the essence of the right to data protection and provide for suitable and specific measures to safeguard the fundamental rights and the interests of the data subject.

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The individual to whom the information relates has consented

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No

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One-off

Safe Setting

Access type

TRE