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PROJECT WITHDRAWN - CCU021: Research into the longer-term effects of COVID-19 in non-hospitalised individuals

Safe People

Organisation name

University of Bristol

Organisation sector

Academic Institute

Applicant name(s)

Nishi Chaturvedi

Jonathan Sterne

Sub-licence arrangements (if any)?

No

Safe Projects

Project ID

CCU021

Lay summary

Physical and mental health consequences of COVID-19 infection, termed long-COVID, occur frequently. Our understanding of long-COVID, including how best to diagnose, risk factors, health and economic consequences, is poor, limiting efforts to help people. We wish to address the following patient defined questions: (1) What is long-COVID and how is it diagnosed? (2) Why have I got long-COVID? (3) What effects will long-COVID have on my health, ability to work and family? What are my chances of recovery? (4) How will this research ensure I am getting the right treatment and support for long-COVID?

Public benefit statement

We will compare rates of symptoms and diseases in people who had COVID-19 with those in the general population, and examine which symptoms occur together. We will study risk factors for long COVID, and longer-term outcomes in people who suffer from it. We will share findings with bodies involved in developing treatment guidelines (NICE, who are also part of this project), with government (via the Chief Scientific Advisor), with the public via social media and other outputs, and the scientific community via research publications. Visit the BHF Data Science Centre website for more detailed information about project outputs. https://bhfdatasciencecentre.org/projects/ccu021/

Technical summary

This project requested access to the following datasets within the Trusted Research Environment(s) for CVD-COVID-UK / COVID-IMPACT: - ENGLAND: - Civil Registration - Deaths - COVID-19 SARI-Watch (formerly CHESS) - Covid-19 Second Generation Surveillance System - Covid-19 UK Non-hospital Antibody Testing Results - Covid-19 UK Non-hospital Antigen Testing Results - COVID-19 Vaccination Adverse Reaction - COVID-19 Vaccination Status - GPES Data for Pandemic Planning and Research (COVID-19) - Hospital Episode Statistics Accident and Emergency - Hospital Episode Statistics Admitted Patient Care - Hospital Episode Statistics Critical Care - Hospital Episode Statistics Outpatients - ICNARC: Intensive Care National Audit and Research Centre - Medicines dispensed in Primary Care (NHSBSA data) - NICOR – MINAP: Myocardial Ischaemia National Audit Project - NICOR – NACRM: National Audit of Cardiac Rhythm Management - NICOR – NACSA: National Adult Cardiac Surgery Audit - NICOR – NCHDA: National Congenital Heart Disease Audit - NICOR – NHFA: National Heart Failure Audit - NICOR – PCI: Percutaneous Coronary Interventions - NICOR – TAVI: Transcatheter Aortic Valve Implantation - Secondary Care Prescribed Medicines (EPMA) - Secondary Uses Services Payment By Results - Sentinel Stroke National Audit Programme Clinical Dataset

Latest approval date

08/11/2021

Safe Data

Data sensitivity level

De-Personalised

Safe Setting

Access type

TRE