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PROJECT WITHDRAWN - CCU025: Has COVID-19 affected the use of guideline-directed medical therapy following coronary artery bypass grafting?
Safe People
Organisation name
University of Glasgow
Organisation sector
Academic Institute
Applicant name(s)
Jill Pell
Salil Deo
Sub-licence arrangements (if any)?
No
Safe Projects
Project ID
CCU025
Lay summary
People with multiple blockages in their heart arteries may need open heart surgery and bypass surgery. For the surgery to remain successful, patients need to take certain types of medicines long-term after their operation. Even before Covid-19 we had insufficient information on how many patients receive and keep taking these medicines. Emerging research has suggested that some cardiovascular medications may increase the risk or severity of Covid-19 infection; others may protect against Covid-19. However, data is limited, and dis-information is rampant. The use of these medications may have changed as a result of the pandemic. The aim of our study is to observe what proportion of patients were prescribed and received the guideline-advised medications after cardiac surgery before and during the Covid-19 pandemic. Our project will help to identify if there has been a change in the use of appropriate medications because of the pandemic. This is very important as being on appropriate medications can help patients feel well and remain protected from heart attacks, stroke and other adverse events. Our study will identify if prescribing of life-saving medications for patients with heart disease has changed over the years before and during the course of the pandemic. Obtaining this information is the first step towards developing solutions to counter any adverse change.
Public benefit statement
Policy makers in the NHS can use our information to develop recommend sharing of key messages and information with patients and to guide targeted educational programmes for general practitioners on appropriate prescribing for patients with heart disease. Visit the BHF Data Science Centre website for more detailed information about project outputs. https://bhfdatasciencecentre.org/projects/ccu025/
Technical summary
This project accessed the following datasets within the Trusted Research Environment(s) for CVD-COVID-UK / COVID-IMPACT: - ENGLAND: - Civil Registration - Deaths - GPES Data for Pandemic Planning and Research (COVID-19) - Hospital Episode Statistics Accident and Emergency - Hospital Episode Statistics Admitted Patient Care - Hospital Episode Statistics Outpatients - Medicines dispensed in Primary Care (NHSBSA data) - Secondary Care Prescribed Medicines (EPMA) - Secondary Uses Services Payment By Results - WALES: - Annual District Death Daily (ADDD) - Annual District Death Extract (ADDE) - COVID-19 Consolidated Deaths (CDDS) - Emergency Department Dataset (EDDS) - Emergency Department Dataset Daily (EDDD) - Outpatient Database for Wales (OPDW) - Outpatient Referral (OPRD) - Patient Episode Dataset for Wales (PEDW) - Welsh Dispensing Dataset (WDDS) - Legacy - Welsh Longitudinal General Practice Dataset (WLGP) - Welsh Primary Care
Latest approval date
14/02/2022
Safe Data
Dataset(s) name
Data sensitivity level
De-Personalised
Safe Setting
Access type
TRE