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CCU030: Examining potential factors underlying the increased risk of severe COVID-19 experienced by people with intellectual and developmental disabilities

Safe People

Organisation name

University of Glasgow

Organisation sector

Academic Institute

Applicant name(s)

Craig Melville

Sub-licence arrangements (if any)?

No

Safe Projects

Project ID

CCU030

Lay summary

People living with intellectual and developmental disabilities (i.e. intellectual disabilities and/or autism) are more likely to be admitted to hospital and die from infection with COVID-19. We do not know why people living with intellectual and developmental disabilities experience poorer outcomes following infection with COVID-19. These poorer outcomes from COVID-19 infection may be caused by people living with intellectual and developmental disabilities: • having higher rates of health problems • being more likely to have two or more serious health problems (multimorbidity) • commonly taking several different medications (polypharmacy). This distinct pattern of health problems experienced by people living with intellectual and developmental disabilities may increase the risk of poorer outcomes from COVID-19 infection. For example, epilepsy is more commonly experienced by people living with intellectual and developmental disabilities, and epilepsy is a known risk factor for premature death from respiratory infections, like COVID-19. Lower rates of vaccination and the type of vaccine that people receive might also influence the higher risk of poorer outcomes.

Public benefit statement

We will investigate whether the complex health problems experienced by people living with intellectual and developmental disabilities and vaccination patterns are linked to poorer COVID-19 outcomes. We hope that the results of this study will help improve outcomes of people living with intellectual and developmental disabilities who are infected with COVID-19.

Latest approval date

22/10/2021

Safe Data

Data sensitivity level

De-Personalised

Safe Setting

Access type

TRE