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Investigating maternal and fetal outcomes for women with Gestational Diabetes Mellitus (GDM).

Safe People

Organisation name

Ulster University

Organisation sector

Academic Institute

Applicant name(s)

Marlene Sinclair

Safe Projects

Project ID

E008

Lay summary

Gestational Diabetes Mellitus (GDM) is glucose intolerance which begins or is first diagnosed during pregnancy (Metzger and Coustan 1998). The number of women being diagnosed with GDM during pregnancy has increased in recent years. The increase in cases of GDM is due in part to a change in diagnostic criteria due to studies such as that by the Hyperglycemia and Adverse Pregnancy Outcomes (HAPO) Study Cooperative Research Group (2008) which identified maternal and fetal risks associated with diabetes at lower glucose levels than that of diabetes diagnosis and the 2015 NICE guidelines. The rate of GDM is also increasing due to growing rates of overweight and obesity (World Health Organisation (WHO) 2015) and higher maternal age at delivery (Snapp and Donaldson 2008). The prevalence of GDM worldwide is estimated to be between 1.7% and 11.6% (Schneider et al. 2012). Due to the increasing levels of GDM and the future risk to the mother of developing type two diabetes (Bellamy et al. 2009), further research is necessary. The overall study aim is to investigate maternal and fetal outcomes for women with Gestational Diabetes (GDM). The study will use data from the Northern Ireland Regional Maternity system (NIMATS) database to create a picture for Northern Ireland on GDM rates and distribution and identify the risk factors. Through the linking of Northern Ireland Regional Maternity system (NIMATS) data with Diamond Data from the Ulster Hospital and data from the prescribing database it will be possible to profile GDM mothers with non GDM mothers and mothers with pre-existing diabetes. The study will also explore the outcomes for the baby when the mother has been diagnosed with GDM. Descriptive statistics and multiple regression analyses will be carried out using SPSS. Descriptive statistics will show if there is a difference in the rate of GDM diagnosis across the Health Trusts in Northern Ireland. In addition, they will show any trends or patterns of GDM levels in the last 3 years. Multiple regression analyses will identify which risk factors are most strongly related with a positive GDM diagnosis.

Public benefit statement

Due to the increasing levels of GDM and the future risk to the mother of developing type two diabetes (Bellamy et al. 2009), further research is necessary. The overall study aim is to investigate maternal and fetal outcomes for women with Gestational Diabetes (GDM). The study will use data from the Northern Ireland Regional Maternity system (NIMATS) database to create a picture for Northern Ireland on GDM rates and distribution and identify the risk factors.

Latest approval date

30/07/2015

Safe Data

Dataset(s) name

Safe Setting

Access type

TRE