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Management of Patent Ductus Arteriosus (PDA) in babies admitted to UK neonatal units: a population-based study using the National Neonatal Research Database

Safe People

Organisation name

Chelsea and Westminster Hospital

Organisation sector

CQC Registered Health or/and Social Care provider

Applicant name(s)

Cheryl Battersby

Funders/ Sponsors

Imperial College London

Safe Projects

Project ID

nnrd11

Lay summary

The aim is to describe the management of patent ductus arteriosus in preterm babies admitted to neonatal units in England and Wales over a 10 year period (2010-2019). Objectives are: To quantify the number and proportion of preterm babies, born <32 weeks gestation, who receive medical and/or surgical intervention for PDA. To describe the infant background and clinical characteristics at the time of medical or surgical PDA intervention and compare them to babies within similar gestational age (GA) groups who did not have an intervention. To determine the postnatal age of medical or surgical PDA intervention. To describe the outcomes of babies treated for PDA (including BPD, NEC, mortality, ventilatory days, brain injury, retinopathy of prematurity) and compare with babies of similar gestational age and neonatal unit with babies those that did not receive PDA intervention To explore the presence of temporal trends and geographical variation in PDA management for the aims 1-4.

Other approval committees

REC reference: 20/LO/0825

Safe Setting

Access type

Release