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UK Neonatal Collaborative Necrotising Enterocolitis Study: using operational clinical data captured electronically at the point of care for surveillance and research (UKNC - NEC Study)

Safe People

Organisation name

Imperial College London

Organisation sector

Academic Institute

Applicant name(s)

Cheryl Battersby

Funders/ Sponsors

NIHR

Safe Projects

Project ID

nnrd45

Lay summary

There is a poor understanding of the epidemiology, multi-factorial aetiology and pathophysiology of Necrotising Enterocolitis (NEC). Strategies for prevention remain elusive, making this an issue of prime importance for neonatal care. There are scant population incidence data, most previous studies have reported by birth weight categories rather than gestational age, and case-definitions have been inconsistent. Interventional studies require good baseline data and an objective case-definition. Overall aims: To establish an objective case-definition for NEC To determine the population incidence of NEC in England To identify enteral-feed related factors that precede onset of NEC in order to inform the design of future interventional randomised controlled trials

Other approval committees

REC reference: 11/LO/1430

Safe Data

Data sensitivity level

Anonymous

Safe Setting

Access type

Release