Strokes can be ischaemic or haemorrhagic in nature, leading to debilitating symptoms which are dependent on the location of the stroke in the brain and the severity of the insult. Stroke care is centred around Hyper-acute Stroke Units (HASU), Acute Stroke and Brain Injury Units (ASU/ABIU) and specialist stroke services. Early presentation enables the use of more invasive treatments to clear blood clots, but commonly strokes present late, preventing their use.

This synthetic dataset represents approximately 29,000 stroke patients. Data includes demography, socioeconomic status, co-morbidities, “time stamped” serial acuity, physiology and treatments, investigations (structured and unstructured data), hospital care processes, and outcomes.

The dataset was created using the Synthetic Data Vault (SDV) package, specifically employing the GAN synthesizer. Real. data was first read and pre-processed, ensuring datetime columns were correctly parsed and identifiers were handled as strings. Metadata was defined to capture the schema, specifying field types and primary keys. This metadata guided the synthesizer in understanding the structure of the data. The GAN synthesizer was then fitted to the real data, learning the distributions and dependencies within. After fitting, the synthesizer generated synthetic data that mirrors the statistical properties and relationships of the original dataset.

Geography: The West Midlands (WM) has a population of 6 million & includes a diverse ethnic & socio-economic mix. UHB is one of the largest NHS Trusts in England, providing direct acute stroke services & specialist care across four hospital sites.

Data set availability: Data access is available via the PIONEER Hub for projects which will benefit the public or patients. Data access can be provided to NHS, academic, commercial, policy and third sector organisations. Applications from SMEs are welcome. There is a single data access process, with public oversight provided by our public review committee, the Data Trust Committee. Contact pioneer@uhb.nhs.uk or visit www.pioneerdatahub.co.uk for more details.

Available supplementary data: Matched controls; ambulance and community data. Unstructured data (images). We can provide the dataset in OMOP and other common data models and can build synthetic data to meet bespoke requirements.

Available supplementary support: Analytics, model build, validation & refinement; A.I. support. Data partner support for ETL (extract, transform & load) processes. Bespoke and “off the shelf” Trusted Research Environment (TRE) build and run. Consultancy with clinical, patient & end-user and purchaser access/ support. Support for regulatory requirements. Cohort discovery. Data-driven trials and “fast screen” services to assess population size.