HDR Gateway logo
HDR Gateway logo

Bookmarks

Moorfields DMO Dataset 003

Population Size

4,166

People

Years

2003

Associated BioSamples

Other

Geographic coverage

https://www.geonames.org/2648147/great-britain.html

Lead time

Not applicable

Summary

The DMO Dataset at Moorfields Eye Hospital NHS Foundation Trust is a longitudinal dataset consisting of routinely collected imaging and clinical metadata from patients receiving treatment for diabetic macular oedema (DMO) from 2001 to the present.

Documentation

The Moorfields DMO Dataset encompasses all patients who have received at least one injection of either Lucentis (ranibizumab) or Eylea (aflibercept) to treat diabetic macular oedema (DMO) at Moorfields Eye Hospital - a leading provider of eye health services in the UK and a world-class centre of excellence for ophthalmic research and education.

These therapies began at Moorfields in 2013, however, the dataset will include any imaging or clinical metadata that is available for these patients prior to that time (for example in patients who were initially monitored for the early forms of the disease prior to receiving treatment). Also of note, this dataset will include data from both eyes in each case - for example, it will include data from fellow eyes that are not receiving injections. For these reasons, the dataset will include longitudinal data from a wide range of diabetic eye disease.

Clinical metadata includes information regarding:

  • patient demographics
  • visual acuities (predominantly measured with Early Treatment Diabetic Retinopathy Study (ETDRS) charts)
  • diabetic retinopathy grading
  • intravitreal therapies and ocular surgeries

Additional information is provided in the ‘technical details’ tab.

The DMO dataset includes eye imaging modalities, such as:

  • Optical coherence tomography (CSO, Heidelberg, Optos, Topcon, Zeiss)
  • Colour fundus photographs (Topcon, Zeiss)
  • Ultra-wide field photographs (Optos, Zeiss)
  • Iris photographs (CSO, Zeiss)
  • Keratoscope topography (CSO)
  • Infrared photographs (Heidelberg, Topcon, Zeiss)
  • Fluorescein angiography (Heidelberg, Optos, Topcon, Zeiss)
  • Indocyanine green angiography (Heidelberg, Optos, Topcon)
  • Fundus autofluorescence (Heidelberg, Optos, Zeiss)

Imaging data from CSO is subject to additional approvals.

As of July 2024, the dataset consisted of 5, 873 eyes receiving Lucentis or Eylea for DMO, over 58, 808 injection episodes, and over 1, 304, 395 ophthalmic images. This is one of the largest single centre databases from patients with DMO and covers more than a decade of follow-up for these patients.

Dataset type
Health and disease
Dataset sub-type
Not applicable
Dataset population size
4,166
Associated media
https://www.insight.hdrhub.org/about-us

Keywords

diabetic macular oedema, Diabetic Retinopathy, Diabetes Mellitus Type 1, Diabetes, diabetic eye disease, aflibercept, ranibizumab, Heidelberg, Topcon, Protocol, Test, Scan, Images, OCT, optic disc, Eylea, Lucentis, DMO, Eye drop, Eye condition, Laterality, Left, Right, Diagnosis, Ocular, Ophthalmology, Visual Acuity, Vision, MEH, IVT, Colour photo, Modality, Injection, Grading, Diabetes Mellitus Type 2, Non-Proliferative Diabetic Retinopathy, Proliferative Diabetic Retinopathy, Background Diabetic Retinopathy, National Screening Grading, Screening Programme, Screening, Referral, Zeiss

Observations

Observed Node
Disambiguating Description
Measured Value
Measured Property
Observation Date

Persons

8,317 Eyes with 1,304,395 Images 5,873 Eyes with 58,808 Injections (Lucentis/Eylea)

4166

Patients

30 Jun 2024

Provenance

Purpose of dataset collection
Study
Collection source setting
Clinic, Secondary care - Accident and Emergency, Secondary care - Outpatients, Secondary care - In-patients
Patient pathway description
The dataset is representative of the entire pathway for patients receiving treatment for diabetic macular oedema (DMO) in the Medical Retina service at Moorfields Eye Hospital NHS Foundation Trust.
Image contrast
Not stated
Biological sample availability
Other

Structural Metadata

Details

Publishing frequency
Continuous
Version
4.0.0
Modified

08/10/2024

Citation Requirements
INSIGHT Health Data Hub

Coverage

Start date

01/01/2003

Time lag
1-2 weeks
Geographic coverage
https://www.geonames.org/2648147/great-britain.html
Minimum age range
26
Maximum age range
91
Follow-up

10 Years

Accessibility

Language
en
Controlled vocabulary
SNOMED CT, DM+D, NHS NATIONAL CODES
Format
csv, image

Data Access Request

Dataset pipeline status
Not available
Access rights
https://www.insight.hdrhub.org/researcher-area
Time to dataset access
Not applicable
Access request cost
https://www.insight.hdrhub.org/contact
Access method category
TRE/SDE
Access service description
INSIGHT has established a Secure Research Environment (SRE) to provide researchers with a computing environment that meets the security levels required by regulation, with the power needed for analysis of large datasets. In addition to the SRE, INSIGHT may provide approved researchers with alternative data access methods, such as data egress, subject to meeting security conditions. For more information please visit our SRE website https://www.insight.hdrhub.org/secure-research-environment.
Jurisdiction
GB-ENG
Data use limitation
General research use
Data use requirements
Project-specific restrictions
Data Controller
Moorfields Eye Hospital NHS Foundation Trust

Dataset Types: Health and disease

Collection Sources: No collection sources listed