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BDR (Brains for Dementia Research)

Population Size

0

People

Population Size statistic card

Years

2009

Years statistic card

Associated BioSamples

None/not available

Associated BioSamples statistic card

Geographic coverage

United Kingdom

Geographic coverage statistic card

Lead time

Data only
Lead time statistic card

Summary

Brains for Dementia Research is an initiative funded jointly by the Alzheimer’s Society and Alzheimer’s Research UK to address the shortage of brain tissue that is so essential for research into dementia. Brain tissue is collected alongside clinical and cognitive information gathered in life. BDR currently networks six brain banks with standardised procedures for brain handling over the sites, ensuring consistency across the sites.

DOI for dataset

https://doi.org/10.48532/006000

Documentation

Living in the UK. Willingness to register for brain donation, and take part in widely used clinical and psychometric measures until the time for brain donation comes. People with a diagnosis of dementia or MCI can register at any age, and those with no diagnosis of memory impairment can register from 65 years old. Exclusion criteria are largely practical and related to the suitability of the donated brain tissue for research. This includes a diagnosis that indicates another brain bank might be more suitable, such as multiple sclerosis. Pre-existing conditions such as schizophrenia, bipolar disorder, brain tumours (including previous radiotherapy treatment to the head), major strokes, aneurysms, and other significant cerebrovascular incidents, can mean a person may not be an ideal ‘control’, or the brain structure is significantly changed. Infections such as meningitis, encephalitis, HIV, prion disease pose an infection risk to all coming in contact with the tissue, so also prevent brain donation.

Dataset type

Health and disease

Keywords

Provenance

Purpose of dataset collection

Research cohort

Biological sample availability

None/not available

Details

Publishing frequency

Continuous

Version

1.0.0

Modified

17/02/2025

Coverage

Start date

01/01/2009

Time lag

Not applicable

Geographic coverage

United Kingdom

Follow-up

Continuous

Accessibility

Language

en

Alignment with standardised data models

OTHER

Controlled vocabulary

OTHER

Format

CSV

Data Access Request

Dataset pipeline status

Available

Access rights

https://portal.dementiasplatform.uk/Apply/DataAccessPolicy

Access method category

TRE/SDE

Access service description

The Data Portal runs its analysis environment through a virtual desktop infrastructure accessible via VMWare software. By analysing the data in the virtual desktop environment you are working on DPUK's servers – meaning there is no physical transfer of data to researchers. The processing capacity enables you to work with large numbers of records and integrate these with the other data modalities that exist in the DPUK cohorts. This solution also offers researchers the freedom to conduct their analyses anywhere with an internet connection.

Data Controller

Newcastle university

Data Processor

Dementias Platform UK

Dataset Types: Health and disease

Dataset Sub-types: Neurological

Collection Sources: