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Extend (The Exeter 10,000 project)
Population Size
0
People
Years
2010
Associated BioSamples
None/not available
Geographic coverage
United Kingdom
Lead time
Data only
Summary
he EXTEND Cohort Study 10,000 is a large-scale, longitudinal research project designed to investigate a wide range of health and lifestyle factors in the general population. It aims to collect data from 10,000 participants to explore the relationships between genetic, environmental, and lifestyle factors and the development of diseases, particularly focusing on chronic diseases like cardiovascular conditions, diabetes, cancer, and mental health disorders.
DOI for dataset
Documentation
A re-contactable research volunteer register and sample biobank of local people with and without health problems who are willing to provide blood and urine samples, have their blood pressure taken and answer simple health and lifestyle questions. Half of the sample taken is used to measure diagnostic markers including blood sugar and cholesterol, which can be shared with the volunteer and the remaining half (requiring consent from the participant) is saved in a biobank. Participants without diabetes will be offered the opportunity to receive a copy of their health measures and blood tests. They may also choose to have these results copied to their doctor. Participants are invited to a return visit (after around three years) to replace samples that have been used up, and update the measurements and other health data recorded The Peninsula Research Bank (PRB) holds the data and banked samples of DNA, urine, serum, plasma and prospectively collected RNA/ whole blood for long term management. The Extend/PRB Biobank enables research into why some people are predisposed to develop a disease as they get older and why some people are protected. The EXTEND register volunteers who are identifiable by phenotype and genotype and agree that they can be contacted to participate in various research projects based on their genetic predisposition have the choice of whether they wish to be involved in studies about Dementia/Alzheimer's disease. Participants can give permission for Researchers to access their medical records.
Dataset type
Health and disease
Dataset sub-type
Not applicable
Associated media
Keywords
Provenance
Purpose of dataset collection
Research cohort
Biological sample availability
None/not available
Structural Metadata
Details
Publishing frequency
Continuous
Version
1.0.0
Modified
17/02/2025
Coverage
Start date
23/03/2010
Time lag
Not applicable
Geographic coverage
United Kingdom
Follow-up
Continuous
Accessibility
Language
en
Alignment with standardised data models
OTHER
Controlled vocabulary
OTHER
Format
CSV
Data Access Request
Dataset pipeline status
Available
Access method category
TRE/SDE
Access service description
The Data Portal runs its analysis environment through a virtual desktop infrastructure accessible via VMWare software. By analysing the data in the virtual desktop environment you are working on DPUK's servers – meaning there is no physical transfer of data to researchers. The processing capacity enables you to work with large numbers of records and integrate these with the other data modalities that exist in the DPUK cohorts. This solution also offers researchers the freedom to conduct their analyses anywhere with an internet connection.
Data Controller
University of Exeter Medical School in partnership with the Royal Devon and Exeter NHS Foundation Trust
Data Processor
Dementias Platform UK