Bookmarks
NIMROD (Neuroimaging of Inflammation in MemoRy and Other Disorders)
Population Size
0
People
Years
2013
Associated BioSamples
None/not available
Geographic coverage
United Kingdom
Lead time
Data only
Summary
he NIMROD (Neuroimaging of Inflammation in MemoRy and Other Disorders) study focuses on understanding the role of brain inflammation in neurodegenerative diseases, particularly Alzheimer’s disease and other memory-related disorders. Using advanced neuroimaging techniques, such as PET scans, the study aims to explore how inflammation in the brain contributes to cognitive decline, memory loss, and the progression of conditions like Alzheimer’s, Parkinson's disease, and mild cognitive impairment.
DOI for dataset
Documentation
The NIMROD (Neuroimaging of Inflammation in Memory and Other Disorders) study aims to understand the role of inflammation in several forms of dementia, memory loss and depression (Alzheimer's disease, AD, dementia with Lewy bodies, DLB, progressive supranuclear palsy, PSP, frontotemporal dementia, FTD, late life depression, LLD, vascular dementia, VaD, mild cognitive impairment, MCI). The study has been set up to investigate the extent and pattern of neuroinflammation in these disorders in relation to: key clinical symptoms, including cognitive impairment, peripheral markers of neuroinflammation, including cytokine levels and state-of-the-art immunoprofiling, structural changes on MRI, including atrophy and vascular (white matter lesion) changes, the extent and pattern of brain amyloid deposition as assessed with amyloid PET imaging, the extent and pattern of tau deposition as revealed with PET. A further aim is to investigate if neuroinflammation can predict subsequent clinical course, including cognitive and functional decline.
Dataset type
Health and disease, Imaging types
Dataset sub-type
Not applicable, Neurological
Keywords
Provenance
Purpose of dataset collection
Study
Biological sample availability
None/not available
Structural Metadata
Details
Publishing frequency
Continuous
Version
1.0.0
Modified
17/02/2025
Coverage
Start date
09/01/2013
Time lag
Not applicable
Geographic coverage
United Kingdom
Follow-up
Continuous
Accessibility
Language
en
Alignment with standardised data models
OTHER
Controlled vocabulary
OTHER
Format
CSV
Data Access Request
Dataset pipeline status
Available
Access method category
TRE/SDE
Access service description
The Data Portal runs its analysis environment through a virtual desktop infrastructure accessible via VMWare software. By analysing the data in the virtual desktop environment you are working on DPUK's servers – meaning there is no physical transfer of data to researchers. The processing capacity enables you to work with large numbers of records and integrate these with the other data modalities that exist in the DPUK cohorts. This solution also offers researchers the freedom to conduct their analyses anywhere with an internet connection.
Data Controller
University of Cambridge
Data Processor
Dementias Platform UK