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Ventilatory strategies and outcomes for patients with COVID: a dataset in OMOP

Population Size

50,902

People

Years

2020 - 2020

Associated BioSamples

None/not available

Geographic coverage

United Kingdom

England

Lead time

Not applicable

Summary

Hospital patients admitted during the COVID pandemic requiring/at risk of requiring ventilatory support. Granular condition, multi-morbidity, interventions and treatments. Serial physiology, blood biomarkers, ITU spells, outcome. Deeply phenotyped.

Documentation

Background. Coronavirus disease 2019 (COVID-19) was identified in January 2020. Currently, there have been more than 6 million cases & more than 1.5 million deaths worldwide. Some individuals experience severe manifestations of infection, including viral pneumonitis, adult respiratory distress syndrome (ARDS) & death. Many patients required ventilatory support including high flow oxygen, continuous positive airway pressure and intubated with or without tracheotomy. Different centres took different approaches to care delivery depending on ITU bed availability. This secondary care COVID OMOP dataset contains granular ventilatory, demographic, morbidity, serial acuity and outcome data in COVID-19.

PIONEER geography The West Midlands (WM) has a population of 5.9 million & includes a diverse ethnic & socio-economic mix. There is a higher than average percentage of minority ethnic groups. WM has a large number of elderly residents but is the youngest population in the UK. Each day >100, 000 people are treated in hospital, see their GP or are cared for by the NHS. The West Midlands was one of the hardest hit regions for COVID admissions in both wave 1 & 2.

EHR. University Hospitals Birmingham NHS Foundation Trust (UHB) is one of the largest NHS Trusts in England, providing direct acute services & specialist care across four hospital sites, with 2.2 million patient episodes per year, 2750 beds & 100 ITU beds. ITU capacity increased to 250 beds during the COVID pandemic. UHB runs a fully electronic healthcare record (EHR) (PICS Birmingham Systems), a shared primary & secondary care record (Your Care Connected) & a patient portal “My Health”. UHB has cared for >5000 COVID admissions to date. This data is in the OMOP format.

Scope: All COVID swab confirmed hospitalised patients to UHB from January – September 2020. The dataset includes highly granular patient demographics & co-morbidities taken from ICD-10 & SNOMED-CT codes. Serial, structured data pertaining to care process (timings, staff grades, specialty review, wards), severity, ventilatory requirements, acuity, all physiology readings (pulse, blood pressure, respiratory rate, oxygen saturations), all blood results, microbiology, all prescribed & administered treatments (fluids, antibiotics, inotropes, vasopressors, organ support), all outcomes.

Available supplementary data: More extensive data including wave 2 patients in non-OMOP form. Ambulance, 111, 999 data, synthetic data.

Available supplementary support: Analytics, Model build, validation & refinement A.I. Data partner support for ETL (extract, transform & load) process, Clinical expertise, Patient & end-user access, Purchaser access, Regulatory requirements, Data-driven trials, “fast screen” services.

Dataset type
Health and disease, Treatments/Interventions
Dataset sub-type
Respiratory
Dataset population size
50,902

Keywords

NHS, acute, exacerbation, COVID, pneumonia, pneumonitis, NEWS2, deterioration, alert, SEWS, oxygen, non-invasive ventilation, high flow oxygen, CPAP, airway pressure, inspiratory pressure, tidal volume, patient, acute hospitals, inpatient, ethnicity, multi-morbidity, blood, biomarkers, physiology, demographics, treatments, therapies, interventions, outcomes, death, longitudinal, vital signs

Observations

Observed Node
Disambiguating Description
Measured Value
Measured Property
Observation Date

Persons

50902 patients including those on ventilation and an unventilated control group

50902

EVENTS

08 Dec 2020

Provenance

Purpose of dataset collection
Other
Source of data extraction
EPR
Collection source setting
Secondary care - Outpatients, Secondary care - In-patients, Community
Patient pathway description
Data focuses on in-patient stay in hospital during the acute episode but can be supplemented on request to include previous and subsequent hospital contacts (including outpatient appointments) and ambulance, 111, 999 data. Data includes those with and without COVID admitted during the first wave of the COVID pandemic.
Image contrast
Not stated
Biological sample availability
None/not available

Structural Metadata

Details

Publishing frequency
Static
Version
1.0.0
Modified

08/10/2024

Distribution release date

11/08/2020

Citation Requirements
This publication uses data from PIONEER, an ethically approved database and analytical environment (East Midlands Derby Research Ethics 20/EM/0158)

Coverage

Start date

01/01/2020

End date

10/09/2020

Time lag
Less than 1 week
Geographic coverage
United Kingdom, England, West Midlands
Minimum age range
18
Maximum age range
108
Follow-up
0 - 6 Months

Accessibility

Language
en
Alignment with standardised data models
OMOP
Controlled vocabulary
SNOMED CT, ICD10
Format
SQL

Data Access Request

Dataset pipeline status
Available
Time to dataset access
Not applicable
Access method category
TRE/SDE
Access service description
Trusted Research Environment on Microsoft Azure cloud server (UK South). Creating the environment will be subject to a charge following approval of data request. The PIONEER team will work with you to ensure the relevant compute power and tooling is available to support your analytical needs.
Data use limitation
Research use only
Data Controller
University Hospitals Birmingham NHS Foundation Trust

Dataset Types: Health and disease, Treatments/Interventions

Dataset Sub-types: Respiratory


Collection Sources: No collection sources listed