Asthma remains a significant clinical and public health challenge for the NHS, affecting millions and contributing to substantial morbidity, healthcare utilisation, and economic burden. Effective management and improved outcomes rely on comprehensive, high-quality data that enable detailed patient phenotyping, longitudinal tracking, and intervention evaluation. This dataset aims to support outcome improvement in asthma care by providing a rich, standardised resource capturing the complexity and diversity of asthma presentations and treatments within a large UK cohort.

Produced for the NIHR Respiratory TRC and Respiratory Catalyst, this OMOP CDM dataset covers 11,834 admissions from 6,502 asthma patients, with demographics, clinical measures, medications, and outcomes for interoperable research. It provides highly granular, interoperable data essential for advanced observational research. The data encompasses demographics, clinical observations and measurements, medication usage, including route of administration, and outcomes such as death and readmission. This comprehensive dataset supports precision medicine approaches and healthcare quality initiatives to improve asthma management.

Geography: The West Midlands (WM) has a population of 6 million & includes a diverse ethnic & socio-economic mix. UHB is one of the largest NHS Trusts in England, providing direct acute services & specialist care across four hospital sites, with 2.2 million patient episodes per year, 2750 beds & > 120 ITU bed capacity. UHB runs a fully electronic healthcare record (EHR) (PICS; Birmingham Systems), a shared primary & secondary care record (Your Care Connected) & a patient portal “My Health”.

Data set availability: Data access is available via the PIONEER Hub for projects which will benefit the public or patients. This can be by developing a new understanding of disease, by providing insights into how to improve care, or by developing new models, tools, treatments, or care processes. Data access can be provided to NHS, academic, commercial, policy and third sector organisations. Applications from SMEs are welcome. There is a single data access process, with public oversight provided by our public review committee, the Data Trust Committee. Contact pioneer@uhb.nhs.uk or visit www.pioneerdatahub.co.uk for more details.

Available supplementary data: Matched controls; ambulance and community data. Unstructured data (images). We can provide the dataset in OMOP and other common data models and can build synthetic data to meet bespoke requirements.

Available supplementary support: Analytics, model build, validation & refinement; A.I. support. Data partner support for ETL (extract, transform & load) processes. Bespoke and “off the shelf” Trusted Research Environment (TRE) build and run. Consultancy with clinical, patient & end-user and purchaser access/ support. Support for regulatory requirements. Cohort discovery. Data-driven trials and “fast screen” services to assess population size.