The iCARE team manage the Imperial Secure Data Environment (SDE), hosted within Imperial College Healthcare NHS Trust (ICHT) NHS infrastructure. The Imperial SDE enables clinicians, researchers and data scientists to access large-scale, highly curated databases for the purposes of research, clinical audit and service evaluation. The SDE enables advanced data analytics through a scalable virtual infrastructure supporting Azure Machine Learning, Python, R and STATA and a large variety of snowflake SQL tooling. (imperial.dcs@nhs.net) The iCARE ICHT tenancy has overarching HRA REC database approval covering all routinely captured information from Imperial College Healthcare Trust (ICHT) Electronic Health Record and 39 linked (at the patient-level) clinical and non-clinical systems. It contains data for all patients from 2015 onwards and is updated weekly as a minimum, and close to real-time when required. This dataset covers outpatient care at IHCT and includes details of emergency care delivered in the EDs at ICHT. It is directly linked to all other iCARE data models and applications are welcome to request linkage between multiple iCARE datasets where necessary to deliver the project. iCARE Data can also be linked to primary care data for the 2.8million population in Northwest London, HRA REC approved, Whole Systems Integrated Care (WSIC) hosted database and other health and social care providers when approved. On a project-by-project basis the model can be expanded to curate and include new data (including multi-modality data), that is either captured routinely or through approved research and clinical trials. There are streamlined processes to approve and curate new data (imperial.dataaccessrequest@nhs.net) and data will always remain hosted in the SDE.