Background: Hospital-Acquired pneumonia (HAP) and Ventilator-Associated pneumonia is an infection of the lungs that is contracted by a patient 2 or more days after an admission. HAP is often more serious than other lung infections due to the nature of the bacteria present in hospital settings, as they are more resistant to treatment than those in the community. HAP typically affects older patients with co-morbidities, those with weakened immune systems or a long-term chronic lung disease. Ventilator-Associated pneumonia is the most common infection associated with a stay in intensive care, with increased long-term mortality and length of stays. These data allow the investigation of the sensitivities of the bacteria, which antibiotics were administered and patient outcomes. The period of data available allows for studying pre- and post- COVID-19 and the impact of ventilation.
PIONEER geography: The West Midlands (WM) has a population of 5.9 million and includes a diverse ethnic and socio-economic mix. EHR: UHB is one of the largest NHS Trusts in England, providing direct acute services and specialist care across four hospital sites, with 2.2 million patient episodes per year, 2750 beds and an expanded 250 ITU bed capacity during COVID. UHB runs a fully electronic healthcare record (EHR) (PICS; Birmingham Systems), a shared primary and secondary care record (Your Care Connected) and a patient portal “My Health”. Scope: All hospitalised patients from 2000 onwards, curated to focus on Hospital and ventilator acquired pneumonia. Longitudinal and individually linked, so that the preceding and subsequent health journey can be mapped and healthcare utilisation prior to and after admission understood. The dataset includes highly granular patient demographics and co-morbidities taken from ICD-10 and SNOMED-CT codes. Serial, structured data pertaining to acute care process (timings, staff grades, specialty review, wards and triage). Along with presenting complaints, outpatients admissions, microbiology results, referrals, procedures, therapies, all physiology readings (pulse, blood pressure, respiratory rate, oxygen saturations and others), and all blood results(urea, albumin, platelets, white blood cells and others). Includes all prescribed and administered treatments and all outcomes. Linked images are also available (radiographs, CT scans, MRI). Available supplementary data: Matched controls; ambulance, OMOP data, synthetic data. Available supplementary support: Analytics, Model build, validation and refinement; A.I.; Data partner support for ETL (extract, transform and load) process, Clinical expertise, Patient and end-user access, Purchaser access, Regulatory requirements, Data-driven trials, “fast screen” services.