REal-time Assessment of Community Transmission (REACT-1) is one of the largest population surveillance studies in the world. It started in April 2020 to measure the prevalence of SARS-CoV-2 in the general population in England. Each month around 150,000 people completed a questionnaire and returned a PCR test.

The study tracked the progress of infection across England. It was commissioned by the Department of Health and Social Care and was carried out between April 2020 and April 2022 in partnership with Imperial College Healthcare NHS Trust and Ipsos MORI.

The partner study, REal-time Assessment of Community Transmission (REACT-2), started in May 2020 to determine the prevalence of and trends in antibodies levels in study participants. This study is also described in the Innovation Gateway.

For further information and the study questionnaires, please see the REACT study website.

We present the full meta-data catalogue in the Innovation Gateway. Researchers external to Imperial College London can apply to access subsets of anonymised data from REACT participants. To access the full REACT dataset on Imperial's TRE, researchers require an affiliation or collaboration with Imperial College London.

REACT has a data sharing agreement with NHS England, details of which can be found under agreement DARS-NIC-431352-G7F1M-v2.2 via https://digital.nhs.uk/services/data-access-request-service-dars/data-uses-register