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A NIHR Birmingham BRC Dataset: Hospital Acquired Pneumonia & Antimicrobial Use
Population Size
22,580
People
Years
2018 - 2022
Associated BioSamples
None/not available
Geographic coverage
United Kingdom
Lead time
1-2 months
Summary
Documentation
Hospital Associated Pneumonia (HAP) is a common healthcare associated infection, thought to affect 1-2% of all UK hospital admissions. Patients with HAP are more likely to need intensive care support and have increased length of stay and mortality rates. Unlike in community-acquired pneumonia, tools to stratify risk or severity are lacking. While there is some understanding of risk-factors that predispose people to HAP, prognostic factors are less well defined. Treatment guidelines suggest broad spectrum antibiotics but there is little understanding of the causative organisms which cause HAP.
To explore HAP, PIONEER, with the NIHR Birmingham BRC Infection and Acute Care theme, have curated a highly granular dataset of 22,580 hospital acquired pneumonia spells. The data includes demography, co-morbidities including Charlson comorbidity index, symptoms, serial physiology and acuity, investigations including microbiology, imaging, medications (dose and route), ward locations including intensive care details and outcomes. The current dataset includes admissions from 01-01-2018 to 31-12-2022 but can be expanded to assess other timelines of interest.
Geography: The West Midlands (WM) has a population of 6 million & includes a diverse ethnic & socio-economic mix. UHB is one of the largest NHS Trusts in England, providing direct acute services & specialist care across four hospital sites, with 2.2 million patient episodes per year, 2750 beds & > 120 ITU bed capacity. UHB runs a fully electronic healthcare record (EHR) (PICS; Birmingham Systems), a shared primary & secondary care record (Your Care Connected) & a patient portal “My Health”.
Data set availability: Data access is available via the PIONEER Hub for projects which will benefit the public or patients. This can be by developing a new understanding of disease, by providing insights into how to improve care, or by developing new models, tools, treatments, or care processes. Data access can be provided to NHS, academic, commercial, policy and third sector organisations. Applications from SMEs are welcome. There is a single data access process, with public oversight provided by our public review committee, the Data Trust Committee. Contact pioneer@uhb.nhs.uk or visit www.pioneerdatahub.co.uk for more details.
Available supplementary data: Matched controls; ambulance and community data. Unstructured data (images). We can provide the dataset in OMOP and other common data models and can build synthetic data to meet bespoke requirements.
Available supplementary support: Analytics, model build, validation & refinement; A.I. support. Data partner support for ETL (extract, transform & load) processes. Bespoke and “off the shelf” Trusted Research Environment (TRE) build and run. Consultancy with clinical, patient & end-user and purchaser access/ support. Support for regulatory requirements. Cohort discovery. Data-driven trials and “fast screen” services to assess population size.
Keywords
Observations
Observed Node | Disambiguating Description | Measured Value | Measured Property | Observation Date |
---|---|---|---|---|
Persons | 22580 HAP spells | 22580 | Count | 19 Sep 2024 |
Provenance
Structural Metadata
Details
31/10/2024
31/10/2024
Coverage
01/01/2018
31/12/2022
Accessibility
Data Access Request
Trusted Research Environments (TRE) are built using Microsoft Azure services and hosted in the UK to provide research teams a safe, secure and agile environment which allows users to quickly analyse, interpret and form an enriched view of primary care information through a range of integrated datasets.
Health data collated from multiple sources is ingested into a secure data lake which will then allow subsets of data to be made available to research teams on approval of a data request. Once approved a customer specific TRE is made available with a standard set of leading analytical tools from Microsoft including Azure Databricks, Azure Machine Learning, Azure SQL and Azure Synapse (for large-scale data warehouses). Specific tools can be provided at an additional cost over the standard platform data access charge and the PIONEER team will work with you to determine your exact needs.
Access to the TRE is managed using the latest virtual desktop technology to provide a safe and secure end-user experience. By utilising leading edge design PIONEER are able to create TREs rapidly to enable us to service any customer requirement.