Frailty is a syndrome of increased vulnerability to incomplete resolution of homeostasis (healing or return to baseline function) following a stressor event (such as an infection or fall) and it is associated with poor outcomes including increased mortality and reduced quality of life. The pathophysiology of frailty is poorly understood. Age and frailty have been proven to be independently predictive of outcomes in patients admitted with an acute illness. In COVID-19, routine frailty identification informed decision making about treatment.

This dataset from 01-03-2020 to 01-04-2022 of 327,346 patients admitted during all waves of the COVID pandemic both with and without COVID-19. The dataset includes granular demographics, frailty scores, physiology and vital signs, all care contacts and investigations (including imaging), all medications including dose and routes, care outcomes, length of stay and outcomes including readmission and mortality.

Geography: The West Midlands (WM) has a population of 6 million & includes a diverse ethnic & socio-economic mix. UHB is one of the largest NHS Trusts in England, providing direct acute services & specialist care across four hospital sites, with 2.2 million patient episodes per year, 2750 beds & > 120 ITU bed capacity. UHB runs a fully electronic healthcare record (EHR) (PICS; Birmingham Systems), a shared primary & secondary care record (Your Care Connected) & a patient portal “My Health”.

Data set availability:  Data access is available via the PIONEER Hub for projects which will benefit the public or patients.  This can be by developing a new understanding of disease, by providing insights into how to improve care, or by developing new models, tools, treatments, or care processes.  Data access can be provided to NHS, academic, commercial, policy and third sector organisations.  Applications from SMEs are welcome.  There is a single data access process, with public oversight provided by our public review committee, the Data Trust Committee.  Contact pioneer@uhb.nhs.uk or visit www.pioneerdatahub.co.uk for more details.

Available supplementary data: Matched controls; ambulance and community data. Unstructured data (images).  We can provide the dataset in OMOP and other common data models and can build synthetic data to meet bespoke requirements.

Available supplementary support: Analytics, model build, validation & refinement; A.I. support.  Data partner support for ETL (extract, transform & load) processes.  Bespoke and “off the shelf” Trusted Research Environment (TRE) build and run.  Consultancy with clinical, patient & end-user and purchaser access/ support.  Support for regulatory requirements.  Cohort discovery. Data-driven trials and “fast screen” services to assess population size.