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Moorfields Dry-AMD Dataset 006

Population Size

7,305

People

Population Size statistic card

Years

2001

Years statistic card

Associated BioSamples

Other

Associated BioSamples statistic card

Geographic coverage

https://www.geonames.org/2648147/great-britain.html

Geographic coverage statistic card

Lead time

2-6 months

Lead time statistic card

Summary

The Dry-AMD Dataset at Moorfields Eye Hospital is a longitudinal dataset consisting of routinely collected data from patients strictly with advanced dry age-related macular degeneration (AMD) and with an absence of the wet form of the disease.

Documentation

The Moorfields Dry-AMD Dataset encompasses all patients with advanced dry AMD, specifically geographic atrophy (GA), and without choroidal neovascularization, at Moorfields Eye Hospital - a leading provider of eye health services in the UK and a world-class centre of excellence for ophthalmic research and education. A detailed description of the dataset definitions can be found below.

Inclusion criteria:

  • a posterior free hand draw label of ‘Geographic’ or (ii) at least one reference in their clinical notes to ‘geographic atrophy’

Exclusion criteria:

  • Patients under the age of 50 at their most-recent imaging event
  • Patients with at least one reference in their clinical notes to ‘Stargardt’
  • Patients with a record of injections of any type
  • Patients with a posterior free hand draw label of ‘Choroidal neovascularization’

The dataset will include any imaging or clinical metadata that is available for these patients. In the instance where only one eye meets the criteria above, both eyes are included in the dataset. For these reasons, the dataset will include longitudinal data from where a patient underwent monitoring during the early and intermediate stages of the disease.

Clinical metadata includes information regarding:

  • patient demographics
  • visual acuities (predominantly measured with Early Treatment Diabetic Retinopathy Study (ETDRS) charts)
  • ocular surgeries

Additional information is provided in the ‘technical details’ tab.

The Dry-AMD dataset includes eye imaging modalities, such as:

  • Optical coherence tomography (CSO, Heidelberg, Optos, Topcon, Zeiss)
  • Colour fundus photographs (Topcon, Zeiss)
  • Ultra-wide field photographs (Optos, Zeiss)
  • Iris photographs (CSO, Zeiss)
  • Keratoscope topography (CSO)
  • Infrared photographs (Heidelberg, Topcon, Zeiss)
  • Fluorescein angiography (Heidelberg, Optos, Topcon, Zeiss)
  • Indocyanine green angiography (Heidelberg, Optos, Topcon)
  • Fundus autofluorescence (Heidelberg, Optos, Zeiss)

Imaging data from CSO is subject to additional approvals.

As of July 2024, the dataset consisted of 11,168 eyes and over 688,018 ophthalmic images.

Dataset type

Health and disease

Dataset sub-type

Not applicable

Dataset population size

7305

Keywords

Observations

Observed Node

Disambiguating Description

Measured Value

Measured Property

Observation Date

Persons

11,168 Eyes with 688,018 Images

7305

Patients

30 Jun 2024

Provenance

Purpose of dataset collection

Study

Collection source setting

Clinic, Secondary care - Accident and Emergency, Secondary care - Outpatients, Secondary care - In-patients

Patient pathway description

The dataset is representative of the entire pathway for patients receiving treatment for age-related macular degeneration (AMD) at Moorfields Eye Hospital NHS Foundation Trust .

Image contrast

Not stated

Biological sample availability

Other

Structural Metadata

Details

Publishing frequency

Continuous

Version

1.0.0

Modified

08/10/2024

Coverage

Start date

01/03/2001

Time lag

1-2 weeks

Minimum age range

38

Maximum age range

103

Follow-up

10 Years

Accessibility

Language

en

Controlled vocabulary

SNOMED CT, DM+D, NHS NATIONAL CODES

Format

CSV, Image

Data Access Request

Dataset pipeline status

Not available

Time to dataset access

2-6 months

Access service description

INSIGHT has established a Secure Research Environment (SRE) to provide researchers with a computing environment that meets the security levels required by regulation, with the power needed for analysis of large datasets. In addition to the SRE, INSIGHT may provide approved researchers with alternative data access methods, such as data egress, subject to meeting security conditions. For more information please visit our SRE website https://www.insight.hdrhub.org/secure-research-environment.

Jurisdiction

GB-GBN

Data use limitation

General research use

Data use requirements

Project-specific restrictions

Data Controller

Moorfields Eye Hospital NHS Foundation Trust

Dataset Types: Health and disease


Collection Sources: Clinic, Secondary care - Accident and Emergency, Secondary care - Outpatients, Secondary care - In-patients

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