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Orchid

ORCHID

Description

ORCHID is a secure data processing environment run by the University of Oxford. It supports the Oxford-Royal College of GPs Clinical Informatics Digital Hub: orchid.phc.ox.ac.uk. ORCHID operates within the Five Safes Framework. The environment currently does not have break-down costs in terms of specific technical requirements, rather these are encompassed into any costs presented to applicants at the application stage.

Active Users: 100 | Active Projects: 50


SAFE People - Login & Access

✓ Accredited Researcher Status Required – Information governance training, data sharing agreements, research project approval

✓ Login: User Registration, VDI over a VPN, Authentication: 2FA

✓ Minimum Requirement: No minimum requirement

✓ International Access: No


SAFE Settings - Compute & Services

✓ Private Cloud.

✓ Virtual Windows desktops as point of entry.

✓ Further compute environments including an R Studio service (8vCPU’s 32GB RAM) and a STATA MP16 environment (8vCPU’s, 32GB RAM). Additional requirements can be supported as required although these need to be discussed at the application stage of the project.

✓ Users are not able to modify the base VM, however they can request additional software or modules via an approval process.

✗ Managed Data analytics capabilities: No

✗ No federated queries

✗ No federated analytics


SAFE Settings - Security Certifications and Measures

✓ Security Certifications: NHS DSPT Toolkit

✓ Security Measures: Independent User Provisioning service, VPN required for access, Password rotation, managed data provisioning, No external network access from secure areas, Secure data ingress/egress, Network security controls.

✓ No VM direct access, Access only through VDI.

✓ No VM access to local media or devices from secure areas (no USB, copy/paste disabled, no internet access).


SAFE Settings - Software access

✓ Default software: Word, Excel, SQL Server Enterprise Manager, Notepad++, 7Zip, Rstudio, STAT MP8 v16, Tableau, MS SQL Server 2016, Matlab, SAS, MS Visual Studio 2019, C/C++/C#, Python

✓ Code/library import: Files can be submitted for approval to the web transfer service.

✓ Collaboration Software: Shared File Store, MS Teams, Local source control, Wiki services.


SAFE Data - Data Access Mechanisms

✓ Data Provisioning: Researchers are able to import data into data analysis software hosted in a secure environment. Read-only access is granted for specific data tables in the database.

✓ Reduce re-identification risk by: Individual training, read-only access control policy, code retention, statistical disclosure control policies

✓ Receive Data: Data can be imported into a secure environment through the web transfer service. All files submitted are subject to an approval process by ORCHID administrators.

✓ Linked Data: Identifiable data fields are hashed using a salt outside of the secure environment and then imported through a secure file share by the ORCHID administrator.

  • ✓ Sensitive Data: Sensitive data can be imported into the secure environment by the ORCHID administrator and added to a file share within the secure environment or added as tables to the secure database.

  • ✓ Open Data: Open data can be transferred into the secure environment using the web transfer tool.

✗ Record Linkage: No record linkage services


SAFE Outputs - Data Output/export

✓ Aggregate level graphs and tables, individual level, anonymised data

✓ Other Export plans: No

✓ Data transmit to other SAFE Settings: no

✓ Statistical Disclosure Control: ORCHID users should make themselves aware of the policy on disclosure controls throughout their use of data. Any data transferred out of ORCHID will be through a authorisation process to ensure controls are met.

Datasets & BioSamples (1)

Publications (2)

Influenza and Respiratory Virus Surveillance, Vaccine Uptake, and Effectiveness at a Time of Cocirculating COVID-19: Protocol for the English Primary Care Sentinel System for 2020-2021.
de Lusignan S, Lopez Bernal J, Byford R, Amirthalingam G, Ferreira F, Akinyemi O, Andrews N, Campbell H, Dabrera G, Deeks A, Elliot AJ, Krajenbrink E, Liyanage H, McGagh D, Okusi C, Parimalanathan V, Ramsay M, Smith G, Tripathy M, Williams J, Victor W, Zambon M, Howsam G, Nicholson BD, Tzortziou Brown V, Butler CC, Butler CC, Joy M, Hobbs FDR.
2021
Risk factors for SARS-CoV-2 among patients in the Oxford Royal College of General Practitioners Research and Surveillance Centre primary care network: a cross-sectional study.
de Lusignan S, Dorward J, Correa A, Jones N, Akinyemi O, Amirthalingam G, Andrews N, Byford R, Dabrera G, Elliot A, Ellis J, Ferreira F, Lopez Bernal J, Okusi C, Ramsay M, Sherlock J, Smith G, Williams J, Howsam G, Zambon M, Joy M, Hobbs FDR.
2020