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NHS England Secure Data Environment (SDE)

Introduction

{"type":"doc","content":[{"type":"paragraph","content":[{"type":"text","text":"The NHS England Secure Data Environment (SDE) is a secure data and research analysis platform. It gives approved researchers with approved projects secure access to NHS healthcare data for healthcare analysis. All patient information in the SDE is pseudonymised. It is part of the NHS Research SDE Network across England."}]},{"type":"paragraph","content":[{"type":"text","text":"To access the NHS England Secure Data Environment a valid Data Sharing Agreement is required. Start the process using our Data Access Request Service here: https://digital.nhs.uk/services/data-access-request-service-dars/process"}]},{"type":"paragraph","content":[{"type":"text","text":"Cost to access: We use a cost recovery model to calculate the charge to assess the NHS England SDE, which can be viewed here: https://digital.nhs.uk/services/secure-data-environment-service"}]},{"type":"paragraph","content":[{"type":"text","marks":[{"type":"bold"}],"text":"SAFE People - Login & Access"}]},{"type":"paragraph","content":[{"type":"text","text":"✓ Applicant Organisations accredited via DSPT" (suggest expanding acronym)"}]},{"type":"paragraph","content":[{"type":"text","text":"✓ Data Access by Applicant Organisation restricted by Data Sharing Agreement (DSA)"}]},{"type":"paragraph","content":[{"type":"text","text":"✓ Applicant Organisation responsible for accrediting end users operating under a DSA"}]},{"type":"paragraph","content":[{"type":"text","text":"✓ End User Access Agreement defines acceptable/expected behaviours"}]},{"type":"paragraph","content":[{"type":"text","text":"✓ Login: Browser based login using 2FA"}]},{"type":"paragraph","content":[{"type":"text","text":"✓ International Access: At a technology-level yes. There are direction sharing agreement restrictions on the use of (some) data"}]},{"type":"paragraph","content":[{"type":"text","marks":[{"type":"bold"}],"text":"SAFE Settings - Compute & Services"}]},{"type":"paragraph","content":[{"type":"text","text":"✓ Data hosted securely on NHSE-managed Amazon Web Services (AWS) accounts"}]},{"type":"paragraph","content":[{"type":"text","text":"✓ Dedicated analysis environment provisioned specifically for each Data Sharing Agreement (DSA)"}]},{"type":"paragraph","content":[{"type":"text","text":"✓ Users operating in one analysis environment have no access to other environments or the public internet"}]},{"type":"paragraph","content":[{"type":"text","marks":[{"type":"bold"}],"text":"SAFE Settings - Security Certifications and Measures"}]},{"type":"paragraph","content":[{"type":"text","text":"✓ Automated scanning & benchmarking against Centre for Internet Security guidelines"}]},{"type":"paragraph","content":[{"type":"text","text":"✓ Static code analysis integrated into build pipelines"}]},{"type":"paragraph","content":[{"type":"text","text":"✓ Infrastructure monitored 24/7 by NHSE Cyber Security Operations Centre (CSOC)"}]},{"type":"paragraph","content":[{"type":"text","text":"✓ Dedicated cyber security allocated to support delivery team"}]},{"type":"paragraph","content":[{"type":"text","text":"✓ Penetration Testing conducted after every significant architectural change"}]},{"type":"paragraph","content":[{"type":"text","text":"✓ Independent Threat Modelling exercise conducted"}]},{"type":"paragraph","content":[{"type":"text","text":"✓ Developers with access to production environment are subject to security vetting"}]},{"type":"paragraph","content":[{"type":"text","text":"SAFE Settings - Software access"}]},{"type":"paragraph","content":[{"type":"text","text":"✓ Direct access to provisioned data only possible via Databricks platform."}]},{"type":"paragraph","content":[{"type":"text","text":"✓ All queries executed via Databricks recorded & auditable in Immuta (access control & auditing component/product)"}]},{"type":"paragraph","content":[{"type":"text","text":"✓ Code packages/libraries made available in the environment are subject to review / approval process"}]},{"type":"paragraph","content":[{"type":"text","marks":[{"type":"bold"}],"text":"SAFE Data - Data Access Mechanisms"}]},{"type":"paragraph","content":[{"type":"text","text":"✓ Data minimised and provisioned in accordance with the approved Data Sharing Agreement (DSA)"}]},{"type":"paragraph","content":[{"type":"text","text":"✓ Data only accessible from DSA-specific analysis environment; data cannot be transferred between analysis environments"}]},{"type":"paragraph","content":[{"type":"text","text":"✓ Identifiable fields pseudonymised in accordance with the DSA."}]},{"type":"paragraph","content":[{"type":"text","text":"✓ Unique pseudo key used for each DSA (a given value will be represented differently in each agreement)"}]},{"type":"paragraph","content":[{"type":"text","text":"✓ Fields containing sensitive data removed from data asset prior to data provisioning process"}]},{"type":"paragraph","content":[{"type":"text","marks":[{"type":"bold"}],"text":"SAFE Outputs - Data Output/export"}]},{"type":"paragraph","content":[{"type":"text","text":"✓ SDE service allows research (with small number suppression) results to be safely exported. This is via an escrow function manned by NHS England employees who examine the artefacts prior to release to the user – based upon an approved, principles-based disclosure control output policy. Patient / row level data cannot be exported."}]},{"type":"paragraph","content":[{"type":"text","text":"✓ Export plans: NHSE are currently exploring a range of safe data outputs types and welcome the opportunity of brining NCS projects into this exploration. We anticipate being able to allow user’s code to be exported in the future."}]},{"type":"paragraph","content":[{"type":"text","text":"✓ Data transmit to other SAFE Settings: We do not provide this service at present. However, ad-hoc requests can be considered via a Service Request"}]},{"type":"paragraph","content":[{"type":"text","text":"✓ Statistical disclosure control process in place"}]}]}

https://digital.nhs.uk/services/secure-data-environment-service

Mental Health Services Data Set - Community

Dataset population size: Unknown

Health and disease

MSDS (Maternity Services Data Set)

Dataset population size: 58,035

Health and disease

Mental Health & Learning Disabilities Dataset v 1 (Sensitive) Events

Dataset population size: Unknown

Health and disease

Mental Health & Learning Disabilities Dataset v 1 (Non-Sensitive) Episodes

Dataset population size: Unknown

Health and disease

Community Services Data Set

Dataset population size: 778,520

Health and disease

Secondary Uses Services Payment By Results

Dataset population size: Unknown

Health and disease

NHS DigiTrials: Clinical Trials

Comparing COVID-19 Vaccine Schedule Combinations (Com-COV)

University of Oxford

A Phase II, randomised, single-blind, platform trial to assess safety, reactogenicity and immunogenicity of COVID-19 vaccines in pregnant women in the United Kingdom (Preg-CoV)

St George's, University of London

Patterning of children and young peoples' mental health before and in the context of Covid-19: findings from the 2017 Mental Health of Children and Young People survey and the 2020 MHCYP Covid-19 follow up survey

NatCen Social Research

Phase II/III Study of AZD2816, a Vaccine for the Prevention of COVID-19 in Adults

AstraZeneca UK Limited

National Gastrointestinal Cancer Audit Programme

Royal College of Surgeons

Comparing COVID-19 Vaccine Schedule Combinations – Stage 2 (Com-COV2)

University of Oxford

Sociodemographic inequality in COVID-19 vaccination coverage amongst elderly adults in England: a national linked data study

Nafilyan V, Dolby T, Razieh C, Gaughan C, Morgan J, Ayoubkhani D, Walker AS, Khunti K, Glickman M, Yates T.

Neurological complications after first dose of COVID-19 vaccines and SARS-CoV-2 infection.

Patone M, Handunnetthi L, Saatci D, Pan J, Katikireddi SV, Razvi S, Hunt D, Mei XW, Dixon S, Zaccardi F, Khunti K, Watkinson P, Coupland CAC, Doidge J, Harrison DA, Ravanan R, Sheikh A, Robertson C, Hippisley-Cox J.

Risk of thrombocytopenia and thromboembolism after covid-19 vaccination and SARS-CoV-2 positive testing: self-controlled case series study.

Hippisley-Cox J, Patone M, Mei XW, Saatci D, Dixon S, Khunti K, Zaccardi F, Watkinson P, Shankar-Hari M, Doidge J, Harrison DA, Griffin SJ, Sheikh A, Coupland CAC.

Obesity, Ethnicity, and Covid-19 Mortality: A population-based cohort study of 12.6 Million Adults in England

Yates T, Summerfield A, Razieh C, Banerjee A, Chudasama Y, Davies MJ, Gillies C, Islam N, Lawson C, Mirkes E, Zaccardi F, Khunti K, Nafilyan V.

Comparative effectiveness of ChAdOx1 versus BNT162b2 COVID-19 vaccines in Health and Social Care workers in England: a cohort study using OpenSAFELY

Hulme WJ, Williamson EJ, Green A, Bhaskaran K, McDonald HI, Rentsch CT, Schultze A, Tazare J, Curtis HJ, Walker AJ, Tomlinson L, Palmer T, Horne E, MacKenna B, Morton CE, Mehrkar A, Fisher L, Bacon S, Evans D, Inglesby P, Hickman G, Davy S, Ward T, Croker R, Eggo RM, Wong AY, Mathur R, Wing K, Forbes H, Grint D, Douglas IJ, Evans SJ, Smeeth L, Bates C, Cockburn J, Parry J, Hester F, Harper S, Sterne JA, Hernán M, Goldacre B.

Association of COVID-19 vaccines ChAdOx1 and BNT162b2 with major venous, arterial, or thrombocytopenic events: A population-based cohort study of 46 million adults in England.

Whiteley WN, Ip S, Cooper JA, Bolton T, Keene S, Walker V, Denholm R, Akbari A, Omigie E, Hollings S, Di Angelantonio E, Denaxas S, Wood A, Sterne JAC, Sudlow C, CVD-COVID-UK consortium.

Introduction

NHS England Secure Data Environment (SDE)

Introduction

Datasets (36)

Datasets

Collections (1)

Analysis Scripts & Software (0)

Data Uses (167)

Publications (70)

Collections

Analysis Scripts & Software

Data Uses

Publications

Introduction

Datasets (36)

Collections (1)

Analysis Scripts & Software (0)

Data Uses (167)

Publications (70)