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CPRD

Introduction

https://www.cprd.com/

Useful links:

https://www.cprd.com/our-services

Datasets(51)

Cancer Registration Data for CPRD Aurum

Dataset population size: 5,544,866

Health and disease

Death Registration data for CPRD GOLD

Dataset population size: 1,341,292

Health and disease

HES Accident and Emergency data for CPRD Aurum

Dataset population size: 36,722,301

Health and disease

Cancer registration data for CPRD GOLD

Dataset population size: 1,122,924

Health and disease

Cancer Patient Experience Survey (CPES) for CPRD GOLD

Dataset population size: 901,965

Health and disease

Quality of Life of Cancer Survivors: Pilot Patient Reported Outcomes(Aurum)

Dataset population size: 3,255,865

Health and disease

Quality of Life of Cancer Survivors: Pilot Patient Reported Outcomes (GOLD)

Dataset population size: 901,965

Health and disease

HES Patient Reported Outcomes Measures (PROMs) data for CPRD GOLD

Dataset population size: 8,024,752

Health and disease

CPRD Aurum Civil Registrations of Death

Dataset population size: 4,888,407

Health and disease

HES Accident and Emergency data for CPRD GOLD

Dataset population size: 8,024,752

Health and disease

CPRD GOLD ICNARC

Dataset population size: 3,149

Health and disease

HES Outpatient data for CPRD GOLD

Dataset population size: 8,024,752

Health and disease

Systemic Anti-Cancer Treatment (SACT) data for CPRD Aurum

Dataset population size: 800,945

Health and disease

CPRD GOLD Ethnicity Record

Dataset population size: 21,715,966

Health and disease

HES Outpatient data for CPRD Aurum

Dataset population size: 34,416,869

Health and disease

CPRD Aurum SGSS

Dataset population size: 1,720,744

Health and disease

CPRD Aurum Small Area data (patient)

Dataset population size: 42,196,349

Health and disease

CPRD GOLD Small Area data (patient)

Dataset population size: 10,404,012

Health and disease

Mental Health Dataset (MHDS) for CPRD Aurum

Dataset population size: 2,080,806

Health and disease

Systemic Anti-Cancer Treatment (SACT) data for CPRD GOLD

Dataset population size: 156,533

Health and disease

HES Admitted Patient Care data for CPRD GOLD

Dataset population size: 8,066,341

Health and disease

HES Admitted Patient Care data for CPRD Aurum

Dataset population size: 41,914,707

Health and disease

CPRD GOLD CHESS

Dataset population size: 5,950

Health and disease

HES Diagnostic Imaging Dataset for CPRD Aurum

Dataset population size: 34,416,869

Health and disease

Mental Health Dataset (MHDS) for CPRD GOLD

Dataset population size: 841,414

Health and disease

HES Patient Reported Outcomes Measures (PROMs) data for CPRD Aurum

Dataset population size: 34,416,869

Health and disease

National Radiotherapy Dataset (RTDS) for CPRD Aurum

Dataset population size: 992,068

Health and disease

Quality of Life of Colorectal Cancer Survivors:Patient Reported Outcomes (Aurum)

Dataset population size: 3,255,865

Health and disease

CPRD Aurum CHESS

Dataset population size: 32,089

Health and disease

Pregnancy Register for CPRD GOLD

Dataset population size: 3,426,686

Health and disease

CPRD COVID-19 Symptoms and Risk Factors Synthetic Dataset

Dataset population size: 4,173,000

Health and disease

CPRD Cardiovascular Disease Synthetic Dataset

Dataset population size: 499,344

Health and disease

Cancer Patient Experience Survey (CPES) for CPRD Aurum

Dataset population size: 3,255,865

Health and disease

CPRD Aurum Ethnicity Record

Dataset population size: 54,186,983

Health and disease

Quality of Life of Colorectal Cancer Survivors: Patient Reported Outcomes (GOLD)

Dataset population size: 901,965

Health and disease

HES Diagnostic Imaging Dataset for CPRD GOLD

Dataset population size: 8,024,752

Health and disease

CPRD Aurum

Dataset population size: 56,609,047

Health and disease

Mother-Baby Link for CPRD GOLD

Dataset population size: 1,691,528

Health and disease

CPRD GOLD

Dataset population size: 21,912,198

Health and disease

CPRD GOLD SGSS

Dataset population size: 378,135

Health and disease

CPRD Aurum ICNARC

Dataset population size: 14,207

Health and disease

Pregnancy Register for CPRD Aurum

Dataset population size: 22,279,945

Health and disease

National Radiotherapy Dataset (RTDS) for CPRD GOLD

Dataset population size: 198,779

Health and disease

CPRD Primary Care and Linked Data OMOP Common Data Model

Dataset population size: 46,624,796

Health and disease

CPRD Primary Care OMOP Common Data Model

Dataset population size: 55,031,347

Health and disease

Mother-Baby Link for CPRD Aurum

Dataset population size: 2,816,882

Health and disease

CPRD Aurum Source file

Dataset population size: 58,667,140

Health and disease

CPRD Primary Care BSA Dispensing Data

Dataset population size: 38,294,389

Health and disease

CPRD Small Area data (practice)

Dataset population size: 78,521,245

Health and disease

CPRD Gold Source file

Dataset population size: 10,914,470

Health and disease

CPRD Aurum BSA Dispensing Data

Dataset population size: 39,846,807

Health and disease

Data uses(135)

Prevalence, incidence, morbidity and mortality of early-onset type 2 diabetes.CPRD

University of Leicester

The Impact of COVID-19 on care for UK patients with chronic obstructive pulmonary disease (COPD) and patients with asthma CPRD

GlaxoSmithKline

Trends in the prevalence of menstrual disorders 2011-2020: a descriptive study of patients presenting to primary care in England CPRD

University of Liverpool

Epidemiology of gout, its treatment and comorbidities - a prospective cohort study using data from Clinical Practice Research Datalink (CPRD)CPRD

University of Nottingham

Managing cardiovascular disease and risk in Covid-19 patients in primary care medicine CPRD

Utrecht University

Comparative effects of different antidiabetic treatments on COVID-19 mortality and vascular outcomes CPRD

London School of Hygiene and Tropical Medicine

Identifying the clinical risks associated with COVID-19 in patients with congenital heart disease and associated co-morbidities CPRD

University of Manchester

Prevalence, prediction, and health outcomes of cardioprotective medication reduction in the older UK population CPRD

University of Oxford

Optimal dynamic treatment regimes for the management of chronic obstructive pulmonary disease (COPD)CPRD

McGill University

Investigating the effect of influenza vaccine on acute cardiovascular events by cardiovascular risk status CPRD

London School of Hygiene and Tropical Medicine

Cost-effectiveness of osteoporotic fracture risk assessment in people with intellectual disabilities CPRD

University of Oxford

Prevalence, Incidence, and healthcare burden of generalised pustular psoriasis, palmoplantar pustulosis, and plaque psoriasis in England CPRD

Boehringer Ingelheim

Patient portal registration and healthcare utilisation outcomes of patients in the NHS General Practice.CPRD

Imperial College London

Impact of underlying diseases, diagnostic processes and treatment on heart failure disease trajectory using international data CPRD

University of Leeds

An assessment of clinical staff workload and predictors of clinical staff workload, in UK primary care settings CPRD

University of Birmingham

Prescription of blood pressure lowering and lipid lowering treatment in the UK and New Zealand: a cross sectional study CPRD

London School of Hygiene and Tropical Medicine

Trends in remote GP consultations and the impact of remote consultations on antibiotic prescribing pre- and during COVID - an observational study CPRD

The Health Foundation

Identifying trends and causes of hospitalisations in people with and without the top 5 chronic conditions: a population-based study CPRD

University of Manchester

Mortality rates, risk factors and treatment patterns in patients diagnosed with moderate-to-very-severe chronic obstructive pulmonary disease in England: a retrospective observational study using CPRD data CPRD

IQVIA

Health resource utilisation and cost burden of individuals with Amyotrophic Lateral Sclerosis (ALS) in England CPRD

Biogen

The effect of diabetes mellitus on perioperative outcomes following colorectal resectional surgery CPRD

University of Nottingham

Effectiveness of triple therapy versus dual therapy in patients with chronic obstructive pulmonary disease who have had one severe or two or more moderate exacerbations within one year CPRD

Imperial College London

Maternal prescriptive drug use: the risks and benefits to mothers and neonates CPRD

University of Bristol

Does ethnicity affect the recognition of palliative care needs? An observational retrospective cohort study CPRD

University of Leeds

Comparison of modelling methods for risk prediction of cardiovascular outcomes in patients with hypertension CPRD

Eli Lilly & Co Ltd

Morbidity, mortality, resource use, and financial cost of pruritus in chronic kidney disease patients in the UK general population: a retrospective matched cohort study CPRD

Pharmatelligence Ltd

The impact of learning disabilities on control of type 2 diabetes risk factors and outcomes in UK primary care CPRD

London School of Hygiene and Tropical Medicine

Developing a methodological framework for the clinical prediction of multimorbidity CPRD

University of Manchester

Examining the change in risk of stroke and bleeding over time in patients with atrial fibrillation: A population-based cohort study using the Clinical Practice Research Datalink CPRD

University of Liverpool

Association between haemoglobin levels and clinical outcomes and healthcare resource use in patients with sickle cell disease in England CPRD

Health IQ

Investigating the influence of ethnicity in Atrial Fibrillation, focusing on the epidemiology, risk factors and outcomes; a population based study.CPRD

University of Leicester

Effectiveness of vaccination policies and current treatment stratification approaches for pneumonia: A regression discontinuity analysis CPRD

University of Heidelberg

Use and effectiveness of non-pharmaceutical interventions for mild to moderate depression CPRD

University of Heidelberg

Incidence and prevalence of mental illness in pregnancy and the first five years after giving birth: a retrospective cohort study using electronic primary care data CPRD

University of Birmingham

Epidemiology and burden of Illness of familial hypercholesterolaemia and hypercholesterolaemia in combination with atherosclerotic cardiovascular disease or atherosclerotic cardiovascular disease risk equivalence.CPRD

Pharmatelligence Ltd

Natural history of coagulopathy and use of anti-thrombotic agents in COVID-19 patients: a cohort study CPRD

University of Oxford

Characterizing the changing morbidity and cause-specific mortality burden of the obesity epidemic in England and the UK CPRD

Imperial College London

Propensity to order diagnostic blood tests in general practices CPRD

University of Birmingham

Completeness and representativeness of ethnicity data in the UK Clinical Practice Research Datalink (CPRD) and Hospital Episode Statistics (HES)CPRD

Clinical Practice Research Datalink (CPRD)

Real-World Effectiveness of Denosumab in Prevention of Fracture among Postmenopausal Osteoporotic Women with FREEDOM Baseline Characteristics CPRD

University of Oxford

A comparison of clinical outcomes, health care resource utilisation and costs for patients with chronic lower limb ulcers including diabetic and venous ulcers when prescribed Prontosan (including solution and gel) and saline solution in England CPRD

Health IQ

The safety of proton pump inhibitors in children with gastroesophageal reflux disease CPRD

McGill University

Long COVID in non-hospitalised individuals: symptoms, risk factors and syndromes CPRD

University of Birmingham

Risk of fractures in cancer survivors in the United Kingdom: a population-based matched cohort study using linked electronic health records databases CPRD

London School of Hygiene and Tropical Medicine

Completeness and representativeness of small area socioeconomic data linked with the UK Clinical Practice Research Datalink (CPRD)CPRD

Clinical Practice Research Datalink (CPRD)

Preventing stroke, premature death and cognitive decline in a broader community of patients with atrial fibrillation using healthcare data for pragmatic research: A randomised controlled trial (DaRe2THINK)CPRD

University of Birmingham

Prediction of which patients with venous thromboembolism may benefit from an extended anticoagulation 3 months post diagnosis CPRD

Bristol-Myers Squibb Pharmaceuticals Ltd (BMS)

Burden of polycystic ovary syndrome during pregnancy and offspring outcomes CPRD

University of Birmingham

Econometric analysis of the distribution of primary and secondary costs and activity for patients with non-communicable diseases CPRD

The Health Foundation

The risk of acute infection in patients with newly diagnosed depression: a cohort study CPRD

Boston Collaborative Drug Surveillance Program (BCDSP)

Evaluating ethnic differences in blood markers of cancer in primary care CPRD

University of Exeter

Multimorbidity and lipid response to statins: a cohort study CPRD

University of Nottingham

The impact of systemic corticosteroids on major adverse cardiovascular events, solid-tumours and mortality in adults: a retrospective cohort study.CPRD

Pharmatelligence Ltd

The Prescribing of Analgesia and Predictors of Long-Term Analgesia Prescriptions in Patients with Inflammatory Arthritis: An Observational Study using the Clinical Practice Research Datalink.CPRD

Keele University

Impact of the COVID-19 Crisis on Treatments, Natural History, Health Care Resource Utilisation, and Medical Cost in Hypertrophic Cardiomyopathy in England CPRD

Bristol-Myers Squibb Pharmaceuticals Ltd (BMS)

The effectiveness of opicapone treatment compared to entacapone in Parkinson's disease using electronic primary healthcare records and linked secondary care data CPRD

Pharmatelligence Ltd

Validation of query definitions for a new or long-term course of antidepressant medications: a descriptive study.CPRD

National Institute for Health and Care Excellence

Estimating national and local prevalence of severe mental illnesses (SMI) and personality disorders (PD) in England: an exploratory study CPRD

Public Health England

The use of locum doctors in the UK National Health System (NHS): understanding and improving the safety and quality of care CPRD

University of Manchester

The Role of Tuberculosis Disease on Non-Communicable Disease Risk: Comparative Analysis of Large Healthcare Databases CPRD

St George's, University of London

Characterisation of multimorbidity clusters and trajectories using data-driven approaches in a nationally-representative population CPRD

Queen Mary University of London

Variation in mental and physical health of children with long-term conditions or disability and their families: a longitudinal cohort study CPRD

University College London

Effectiveness of Indapamide Sustained Released on top of Perindopril on blood pressure change: a methodological study to validate effect of anti-hypertensive drugs in Clinical Research Practice Datalink CPRD

Institut de Recherches Internationales Servier (IRIS)

Mortality and associated risk factors in individuals with and without type 1 and type 2 diabetes: A matched retrospective cohort study.CPRD

University of Leicester

Predictors and outcomes of traumatic brain injury (concussion) in children CPRD

University of Bristol

Incidence and prevalence of Antiphospholipid Syndrome in United Kingdom.CPRD

UCB Biopharma SRL

The clinical and economic burden of antibiotic use among paediatric patients with Varicella infection: a retrospective cohort analysis of real-world data in the UK CPRD

Merck & Co. Inc

The nexus of diabetes, hypertension, and depression and its contribution to multimorbidity in United Kingdom CPRD

Imperial College London

Retrospective database study to describe healthcare resource utilization in patients on antimuscarinics with overactive bladder in England CPRD

Astellas Pharma Europe Ltd

The impact of systemic corticosteroids on diabetes mellitus and osteoporosis in adults: a retrospective cohort study CPRD

AstraZeneca UK Limited

Evaluating the risk of incident cardiovascular disease and cardiovascular drug prescribing patterns in patients with liver disease CPRD

University College London

Multimorbidity and health care outcomes in patients with Rheumatoid Arthritis and Psoriatic Arthritis CPRD

University of Glasgow

The impact of area level deprivation and geographical variation on survival and resource use in patients with colorectal, gastro-oesophageal, lung or ovarian cancer in England.CPRD

University of Exeter

Investigate the determinants and trends of heart failure and other major cardiovascular events in diabetes patients and their subsequent prognosis within the UK population CPRD

University of Leicester

Healthcare utilisation, symptoms, prescriptions and new disease in people with COVID-19 managed in the community or hospital.CPRD

Imperial College London

Epidemiology and treatment of Myasthenia Gravis (MG): A retrospective study in Clinical Practice Research Datalink (CPRD) and Hospital Episodes Statistics (HES)CPRD

UCB Celltech

Can we use routinely collected primary care medical records to assess and explain variations in major lower extremity amputation rates across the England?CPRD

University of Leicester

The Impact of COVID-19 lockdown on the lives of People with Obesity (PwO): A UK primary care based study CPRD

University of Leicester

Prevalence and healthcare utilization of patients with Eosinophilic granulomatosis with polyangiitis (EGPA) in the Clinical Practice Research Datalink database CPRD

GlaxoSmithKline

WEiGht changes, caRdio-metabolic risks and mortality in patients with hypErThyroidism; all-cohort natural history and comparison of treatment effects in a CPRD-HES linked study. EGRET study CPRD

University of Birmingham

Characterising the young chronic obstructive pulmonary disease (COPD) patient in the United Kingdom: A descriptive study looking at clinical and aetiological factors utilising Clinical Practice Research Datalink (CPRD)CPRD

Boehringer Ingelheim

Respiratory Syncytial Virus (RSV) infections in England: estimating the burden of antibiotic prescriptions, healthcare utilisation and associated costs.CPRD

Imperial College London

Outcomes of maternal epilepsy and antiepileptic medications during pregnancy (PREPArE)CPRD

University of Bristol

Temporal trends in the incidence of common mental disorders in the United Kingdom by sociodemographic group (2000-2020)CPRD

University College London

The development of risk-stratified blood-test monitoring strategies for common inflammatory conditions treated with immune suppressing drugs CPRD

University of Nottingham

CORYLUS UK: A retrospective observational cohort study of the impact of COVID-19 on systemic lupus erythematosus patients in England using data from linked primary and secondary care databases CPRD

Health IQ

Effectiveness and safety of apixaban vs rivaroxaban in patients with Atrial Fibrillation and Diabetes Mellitus CPRD

McGill University

Sulfonylureas versus metformin as initial treatment for type 2 diabetes and the risk of ventricular arrhythmia: A population-based cohort study CPRD

McGill University

A Case Control and Cohort Design Study, using Multi-state Models, Analysis of Treatment Patterns in Chronic Obstructive Pulmonary Disease and Asthma.CPRD

Twist Health

Artificial intelligence for identifying new disease clusters in patients with immune-mediated inflammatory conditions: A Proof-of-Concept Study CPRD

University of Bath

CharacTeristics of treAtment response to hIgh dose inhaled corticosteroids(ICS)+Long acting B2 agonist(LABA) vs medium or high dOse ICS+LABA+long acting muscarinic antagonist in patients with uncontRolled moderate to severe asthma on medium dose ICS+LABA CPRD

University of Oxford

Association between weight loss and fertility in women diagnosed with polycystic ovary syndrome and living with overweight or obesity CPRD

Novo Nordisk

Burden of Disease and Treatment Patterns for Patients with Hip and Knee Osteoarthritis in the United Kingdom CPRD

Evidera

Healthcare utilisation, symptoms, prescriptions and new disease in people with COVID-19 managed in the community or hospital CPRD

Imperial College London

Ethnic differences in healthcare utilisation and care quality among people with multiple conditions CPRD

The Health Foundation

Association of physical conditions with challenging behaviours in people with intellectual disabilities: a longitudinal cohort study of a national sample of primary-care patients in England using the Clinical Practice Research Datalink CPRD

University of Glasgow

Investigating whether in utero exposure to maternal antihypertensive medication is associated with adverse pregnancy outcomes and adverse health and neurodevelopmental outcomes in offspring CPRD

University of Glasgow

Does the association between multiple long-term conditions and mortality risk vary across sociodemographic groups?CPRD

The Health Foundation

Prognostic significance of initiating loop diuretics and its relationship to heart failure CPRD

University of Glasgow

Use of renin-angiotensin-aldosterone system inhibitors and the risk of acute pancreatitis CPRD

McGill University

The direct and indirect effects of Covid-19 on long-term conditions: A retrospective cohort study using primary and secondary care electronic health records CPRD

University of Birmingham

Association between weight loss and healthcare resource utilization in adults living with obesity CPRD

Novo Nordisk

Investigating whether in utero exposure to maternal psychotropic medication is associated with adverse pregnancy outcomes and adverse health and neurodevelopmental outcomes in offspring CPRD

University of Glasgow

COVID-19 recording in Clinical Practice Research Datalink primary care data and linked Second Generation Surveillance System SARS-CoV-2 virology test data CPRD

Clinical Practice Research Datalink (CPRD)

Evaluation of de novo diabetes or diabetes worsening in metastatic castration resistant prostate cancer patients treated with abiraterone acetate compared with enzalutamide in England.CPRD

Astellas Pharma Europe Ltd

Trends of gabapentinoid prescribing associated overdose and mortality in chronic pain patients and the impact of gabapentinoid classification as a controlled drug CPRD

University of Nottingham

Moderating effects of intellectual disabilities on mortality among people with autism: a retrospective cohort study of a national sample of primary-care patients in England using the Clinical Practice Research Datalink CPRD

University of Glasgow

Incidence and prevalence of heart failure in patients with idiopathic pulmonary fibrosis (IPF) between 2010 - 2019 and the impact of heart failure treatment on IPF mortality: a population-based study using CPRD Aurum CPRD

Imperial College London

Prevalence and incidence of mental health conditions in children and young people with intellectual disabilities in England CPRD

University of Glasgow

Real world evidence in asthma and chronic obstructive pulmonary disease to understand the burden of COVID-19 infection in United Kingdom CPRD

AstraZeneca UK Limited

Investigating epilepsy-related mortality among children and young people with intellectual disabilities and co-occurring epilepsy: a record linkage cohort study CPRD

University of Glasgow

Assessing the quality and uptake of incentivised physical health checks for people with serious mental illness CPRD

University of York

Overactive bladder anticholinergics and risk of incident dementia: a cohort study design using a triangulation approach CPRD

University of East Anglia

Developing personalised risk prediction for women at increased risk of Vulval Cancer CPRD

University of Manchester

Cohort study of risk factors of acute and chronic cardiovascular events in COVID-19 patients CPRD

King's College London

Risk of Abnormal Uterine Bleeding associated with direct oral anticoagulants compared with Vitamin K antagonists CPRD

McGill University

A longitudinal study of the association between depression and glycaemic control in people with diabetes in primary care CPRD

King's College London

A retrospective database analysis to estimate the burden of pneumococcal disease in children 0-17 years in England CPRD

Merck & Co. Inc

Risk of tendon disorders and Psoriatic arthritis with fluoroquinolone prescriptions in Psoriasis patients CPRD

University of Glasgow

Prediction of significant bleeding during anticoagulant use in patients with cancer-related venous thromboembolism: an English cohort study.CPRD

Bristol-Myers Squibb Pharmaceuticals Ltd (BMS)

Understanding associations between cardiometabolic and cardiac health, and risk of dementia CPRD

University of Glasgow

Urban-rural comparison of access to care and health outcomes for five major health conditions related to cardio-metabolic diseases, mental health and infectious diseases in England CPRD

University of Heidelberg

PRECISION-Predicting Risk of Endometrial Cancer in aSymptomatIc wOmeN CPRD

University of Manchester

The impact of timely diagnosis and recurrent health seeking behaviour on the subsequent clinical course of Inflammatory Bowel Disease: A UK population based study CPRD

Imperial College London

Is there an association between antibiotic exposure and Parkinson disease?CPRD

Rutgers, The State University of New Jersey

Comparability and Relative Effectiveness of Osteoporosis Treatment Groups in European Clinical Practice CPRD

Amgen Ltd

Trends and factors associated with prescription opioid utilisation, dependence and deaths in patients with rheumatic and musculoskeletal diseases CPRD

University of Manchester

Comorbidity among patients receiving opioid substitution therapy: examination of primary and secondary healthcare utilisation, cost of care, drug-drug interactions and mortality risk.CPRD

University of Manchester

Incidence, Prevalence of Multiple Sclerosis in CPRD – Burden of Mortality, Infection and Cancer Among Patients With Multiple Sclerosis CPRD

Roche

A retrospective, observational, real world study to describe the treatment pathway, healthcare resource utilisation, and clinical outcomes in patients with metachromatic leukodystrophy CPRD

Pharmatelligence Ltd

Prevalence estimate of atherosclerotic cardiovascular disease, atherosclerotic cardiovascular disease -risk equivalent and familial hypercholesterolaemia patients with elevated low-density lipoprotein cholesterol.CPRD

Pharmatelligence Ltd

Understanding clusters and mechanisms of complex multimorbidity in people with common allergic conditions CPRD

London School of Hygiene and Tropical Medicine

The descriptive epidemiology of Adverse Events of Special Interest for COVID-19 and other vaccines in the general population and after seasonal influenza and COVID-19 disease CPRD

University of Oxford

Lifelong Adverse health ouTcomes Especially dementia risk following Traumatic Brain Injury (LATE-TBI)CPRD

University of Glasgow

Direct oral anticoagulants (DOAC) dosing patients with non-valvular atrial fibrillation (NVAF): a retrospective cohort study using the Clinical Practice Research Datalink (CPRD) Gold database CPRD

LA-SER Europe Ltd

Associated data uses(2)

To determine whether four medications (clopidogrel, warfarin, nitrates, and prednisolone) associated with increased risk of upper gastrointestinal cancer from a study that screened 250 prescription medications using GP data from Scotland (PCCIUR) are also associated with increased risk in the CPRD NHS England Secure Data Environment (SDE)

CPRD, Queen’s University Belfast

Resource use and survival evaluation using UK data from CPRD, HES and NCRAS databases among patients with Neuroendocrine Tumours (NETs): A retrospective analysis NHS England Secure Data Environment (SDE)

CPRD, Novartis Ltd

Associated analysis scripts, tools and software(1)

Code for 'Optimal risk assessment intervals for primary prevention of cardiovascular disease: a population-based two-stage landmarking study'

Jessica Barrett

Created - 11 November 2025

Associated publications(10)

Mortality of Care Home Residents and Community-Dwelling Controls During the COVID-19 Pandemic in 2020: Matched Cohort Study

Gulliford MC, Prevost AT, Clegg A, Rezel-Potts E.

Observational methods for COVID-19 vaccine effectiveness research: a trial emulation and empirical evaluation

Català M, Burn E, Rathod-Mistry T, Xie J, Delmestri A, Prieto-Alhambra D, Jödicke AM.

"Take up to eight tablets per day": Incorporating free-text medication instructions into a transparent and reproducible process for preparing drug exposure data for pharmacoepidemiology.

Jani M, Yimer BB, Selby D, Lunt M, Nenadic G, Dixon WG.

Using Polygenic Risk Scores for Prioritizing Individuals at Greatest Need of a Cardiovascular Disease Risk Assessment.

Chung R, Xu Z, Arnold M, Ip S, Harrison H, Barrett J, Pennells L, Kim LG, Di Angelantonio E, Paige E, Ritchie SC, Inouye M, Usher-Smith JA, Wood AM.

A Harmonised Approach to Curating Research-Ready Datasets for Asthma, Chronic Obstructive Pulmonary Disease (COPD) and Interstitial Lung Disease (ILD) in England, Wales and Scotland Using Clinical Practice Research Datalink (CPRD), Secure Anonymised Information Linkage (SAIL) Databank and DataLoch.Health Data Research UK

Hatam S, Scully ST, Cook S, Evans HT, Hume A, Kallis C, Farr I, Orton C, Sheikh A, Quint JK.

Cancer incidence and competing mortality risk following 15 presenting symptoms in primary care: a population-based cohort study using electronic healthcare records.Health Data Research UK

Barclay ME, Renzi C, Harrison H, Torralbo A, White B, Ip SHY, Usher-Smith J, Lange J, Pashayan N, Denaxas S, Wood AM, Antoniou A, Lyratzopoulos G.

Determining prescriptions in electronic healthcare record data: methods for development of standardized, reproducible drug codelists.Health Data Research UK

Graul EL, Stone PW, Massen GM, Hatam S, Adamson A, Denaxas S, Peters NS, Quint JK.

Identifying clinical features in primary care electronic health record studies: methods for codelist development.Health Data Research UK

Watson J, Nicholson BD, Hamilton W, Price S.

Validation of the Recording of Acute Exacerbations of COPD in UK Primary Care Electronic Healthcare Records.Health Data Research UK

Rothnie KJ, Müllerová H, Hurst JR, Smeeth L, Davis K, Thomas SL, Quint JK.

Optimal risk assessment intervals for primary prevention of cardiovascular disease: a population-based two-stage landmarking study.

Gu Z, Gasperoni F, Paige E, Sweeting M, Usher-Smith J, Poppe K, Stevens D, Arnold M, Di Angelantonio E, Wood AM, Barrett JK.

Collections(1)

Clinical Practice Research Datalink (CPRD)

Associated collections(5)

HERON-UK (Health Data Research UK OMOP Network)

Dementia Trials Accelerator

Cancer Data-Driven Detection (CD3) Programme

Research Study Cohorts on the Gateway

Dementia Trials Accelerator

Login update

CPRD

Datasets

Collections

Analysis Scripts & Software

Data Uses

Publications