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The NHS Research Secure Data Environment (SDE) Network

The NHS Research Secure Data Environment (SDE) Network

Introduction

The NHS Research Secure Data Environment (SDE) Network helps approved researchers by simplifying and accelerating secure access to the health and social care data they need. It is designed to be the default route for accessing NHS data for research and will drive federation and interoperability in two main ways:

  • aggregating data at a scale much larger than previously possible across the NHS, reducing data silos and landscape complexity.
  • embedding interoperability and enabling federated analytics across multiple platforms – including genomics, imaging, and Electronic Health Records.

National coverage

The SDE Network includes the NHS England SDE and 11 regional SDE teams, covering all of England through a federated approach.

Rapid access

By using the Health Data Research Gateway as its ‘front door’, the SDE Network aims to de-fragment health data assets and make searching for data easier for researchers. The SDE Network provides rapid access to data that has both breadth and depth across care settings and data types (multi-modality), including reliably uniting primary and secondary care datasets.

Supporting research

The NHS Research SDE Network can support research use cases from AI development and epidemiology to health systems research and real-world studies. It is a foundational layer to a strong, data and evidence-based, research and innovation ecosystem.

Find out more

Information about the services provided by members of the NHS Research SDE Network is available here.

Data Custodians (12)

East Midlands Secure Data Environment (SDE)
Datasets (9)Data Use (2)
Tools (0)Publications (0)
Collections (2)
NHS England Secure Data Environment (SDE)
Datasets (36)Data Use (193)
Tools (0)Publications (64)
Collections (12)
Kent, Medway and Sussex Secure Data Environment (SDE)
Datasets (2)Data Use (0)
Tools (0)Publications (0)
Collections (1)
North West Secure Data Environment (SDE)
Datasets (0)Data Use (0)
Tools (0)Publications (0)
Collections (0)
Wessex Secure Data Environment (SDE)
Datasets (0)Data Use (0)
Tools (0)Publications (0)
Collections (0)
South West Secure Data Environment (SDE)
Datasets (0)Data Use (0)
Tools (0)Publications (0)
Collections (0)

Datasets (121)

Computational modelling in critical illness
Dataset population size: 100
Health and disease
MR measures of liver fibrosis (MRker)
Dataset population size: 115
Health and disease
UK BioLAM
Dataset population size: 300
Health and disease
Crohn's Disease Metabolic Syndrome & Related Disease Outcomes
Dataset population size: Unknown
Health and disease

Analysis Scripts & Software (2)

Publications (66)

Sociodemographic inequality in COVID-19 vaccination coverage amongst elderly adults in England: a national linked data study
Nafilyan V, Dolby T, Razieh C, Gaughan C, Morgan J, Ayoubkhani D, Walker AS, Khunti K, Glickman M, Yates T.
Neurological complications after first dose of COVID-19 vaccines and SARS-CoV-2 infection.
Patone M, Handunnetthi L, Saatci D, Pan J, Katikireddi SV, Razvi S, Hunt D, Mei XW, Dixon S, Zaccardi F, Khunti K, Watkinson P, Coupland CAC, Doidge J, Harrison DA, Ravanan R, Sheikh A, Robertson C, Hippisley-Cox J.
Risk of thrombocytopenia and thromboembolism after covid-19 vaccination and SARS-CoV-2 positive testing: self-controlled case series study.
Hippisley-Cox J, Patone M, Mei XW, Saatci D, Dixon S, Khunti K, Zaccardi F, Watkinson P, Shankar-Hari M, Doidge J, Harrison DA, Griffin SJ, Sheikh A, Coupland CAC.
Obesity, Ethnicity, and Covid-19 Mortality: A population-based cohort study of 12.6 Million Adults in England
Yates T, Summerfield A, Razieh C, Banerjee A, Chudasama Y, Davies MJ, Gillies C, Islam N, Lawson C, Mirkes E, Zaccardi F, Khunti K, Nafilyan V.
Comparative effectiveness of ChAdOx1 versus BNT162b2 COVID-19 vaccines in Health and Social Care workers in England: a cohort study using OpenSAFELY
Hulme WJ, Williamson EJ, Green A, Bhaskaran K, McDonald HI, Rentsch CT, Schultze A, Tazare J, Curtis HJ, Walker AJ, Tomlinson L, Palmer T, Horne E, MacKenna B, Morton CE, Mehrkar A, Fisher L, Bacon S, Evans D, Inglesby P, Hickman G, Davy S, Ward T, Croker R, Eggo RM, Wong AY, Mathur R, Wing K, Forbes H, Grint D, Douglas IJ, Evans SJ, Smeeth L, Bates C, Cockburn J, Parry J, Hester F, Harper S, Sterne JA, Hernán M, Goldacre B.
Association of COVID-19 vaccines ChAdOx1 and BNT162b2 with major venous, arterial, or thrombocytopenic events: A population-based cohort study of 46 million adults in England.
Whiteley WN, Ip S, Cooper JA, Bolton T, Keene S, Walker V, Denholm R, Akbari A, Omigie E, Hollings S, Di Angelantonio E, Denaxas S, Wood A, Sterne JAC, Sudlow C, CVD-COVID-UK consortium.